New gene-editing approach could be used to eliminate disease-causing mutations from pedigree dog breeds or even from clones of individual dogs
Life
22 July 2022
Gene-edited beagle puppies Okjae Koo/ToolGen
Two beagle dogs have been born in South Korea from cloned skin cells altered by CRISPR gene editing. CRISPR-edited dogs have previously been created by altering fertilised eggs, but this is the first time they have been created by cloning.
Many pure-bred pedigree dogs have disease-causing mutations. Gene editing could be used to eliminate these without affecting other traits. So, for this purpose, the cloning approach has advantages over the editing-eggs approach, says Okjae Koo at biotech company ToolGen.”[It] is more reliable for generating various pure-bred …
Offer ends 31/08/2022. *Cancel anytime within 14 days of payment to receive a refund on unserved issues.
Existing subscribers, please log in with your email address to link your account access.
Inclusive of applicable taxes (VAT)
